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Treatments/Skin & Health

Skin & Health

Mesotherapy

Non-surgical cosmetic medicine for aesthetic medicine and dermatology

Mesotherapy is a minimally invasive skin rejuvenation treatment using a series of precise micro-injections to deliver a customised blend of active ingredients into the superficial layers of the skin. Depending on your individual treatment plan, the formulation may contain ingredients such as hyaluronic acid, vitamins, minerals, amino acids and other skin-supporting compounds.

Hair mesotherapy with the U225 Meso Gun at YourHealthFirst Clinic — nourish, stimulate, strengthen

Mesotherapy in London – Skin Rejuvenation & Hydration

At YourHealthFirst Clinic on Wimpole Street, London, mesotherapy can be performed using the U225 Meso Gun, a specialised medical mesotherapy device designed to deliver controlled, rapid micro-injections with a high degree of consistency and precision. The treatment can also be performed using a manual micro-injection technique, depending on the area being treated, the skin condition and the chosen formulation.

Face and skin mesotherapy with the U225 Meso Gun at YourHealthFirst Clinic — hydrate, rejuvenate, stimulate, restore

How does Mesotherapy work?

Mesotherapy works by introducing small amounts of carefully selected ingredients directly into the skin rather than relying solely on topical skincare products. The aim is to improve skin hydration, radiance, texture and overall quality, while supporting the skin's natural regenerative processes.

The U225 Meso Gun delivers a rapid series of very fine micro-injections into the superficial skin layers. This allows the treatment to be administered evenly and precisely across the selected area.

What can Mesotherapy help with?

Mesotherapy may be suitable for people concerned about dull or tired-looking skin, dehydration, uneven skin texture, fine lines and loss of skin radiance. Depending on the formulation selected, it may also form part of a personalised treatment plan for areas affected by pigmentation, superficial skin imperfections or signs of ageing.

The treatment can be tailored to different areas, including the face, neck, décolletage and other areas of the body, depending on your individual needs.

Mesotherapy with the U225 Meso Gun

At YourHealthFirst Clinic, we use the U225 Meso Gun when appropriate to provide controlled micro-injections over the treatment area. This technique allows the practitioner to deliver the selected mesotherapy formulation consistently and accurately while treating larger areas efficiently.

For some patients, manual micro-injection mesotherapy may be more appropriate. Your treatment technique and formulation are selected according to your skin, the area being treated and your desired outcome.

Mesotherapy and Microneedling Techniques

Depending on your individual treatment plan, mesotherapy can be delivered using different techniques.

U225 Meso Gun: Delivers a series of controlled, precise micro-injections into the superficial layers of the skin, allowing the selected mesotherapy formulation to be distributed evenly across the treatment area.
Manual Micro-Injections: For certain areas and treatment protocols, mesotherapy can also be administered manually using a very fine needle, allowing precise placement of the selected formulation.
Microneedling Pen: Where appropriate, selected mesotherapy formulations can also be incorporated into a microneedling treatment using a professional microneedling pen. The pen creates controlled microscopic channels in the skin, supporting the absorption of suitable topical formulations and stimulating the skin's natural regenerative response.

The technique used will depend on your skin condition, treatment area, formulation and desired outcome.

Your Mesotherapy Questions Answered

Is Mesotherapy painful?: Mesotherapy is generally well tolerated. Because it involves multiple very fine injections, some patients may experience mild discomfort, particularly in more sensitive areas. A topical local anaesthetic cream can be considered where appropriate to improve comfort during treatment.
How long does Mesotherapy take?: A typical mesotherapy treatment takes approximately 30–45 minutes, depending on the area being treated and the treatment protocol.
Is there any downtime?: Mesotherapy usually involves minimal downtime, although temporary redness, mild swelling, tenderness or small areas of bruising can occur at the injection points. These effects generally settle relatively quickly, but recovery varies according to the individual and the treatment area.
When will I see results?: Some patients notice an improvement in skin hydration and radiance relatively soon after treatment, while further improvements in skin quality may develop progressively following a course of treatments. The number and frequency of sessions will depend on your skin condition, the formulation used and your treatment goals. Rather than applying the same course to everyone, we recommend a personalised treatment plan following consultation and assessment.

Can Mesotherapy be combined with other aesthetic treatments?

Yes. Mesotherapy can be incorporated into a broader skin rejuvenation programme and may be combined with treatments such as PRP therapy, microneedling, anti-wrinkle injections or dermal fillers, where clinically appropriate.

Your treatment plan will be designed around your skin concerns, treatment history and desired outcome.

At YourHealthFirst Clinic, mesotherapy is carried out as part of a personalised aesthetic and regenerative skin treatment approach. Each treatment is selected following an assessment of your skin and your individual objectives, with the aim of achieving natural-looking improvements in hydration, texture, radiance and overall skin quality.

Book a Mesotherapy consultation in London at YourHealthFirst Clinic, Wimpole Street.

Suitable For

  • Adults with dull, dehydrated or uneven skin
  • Those with acne scarring, fine lines or stretch marks
  • Patients seeking skin brightening or anti-ageing treatment
  • Anyone wanting a customised, multi-ingredient skin, body or hair booster

Key Facts

Results

Visible improvement after 2–3 sessions; a course of 6–8 sessions is advised

Starting From

£250 per session / £800 course of 4

Location

2 Wimpole Street, London W1G 0EB

Book a Consultation

Begin with a personal consultation with Sofia to discuss your goals and confirm suitability.

Key Benefits

  • Remove fat in areas like the stomach, thighs, buttocks, hips, legs, arms and face
  • Reduce cellulite and stretch marks
  • Fade superficial wrinkles and lines
  • Tighten loose skin, re-contour the body
  • Address loss of glow, loss of tone, dry and irritated skin
  • Lighten pigmented skin and age spots
  • Treat alopecia, a condition that causes hair loss
  • Reduce dark circles under eyes, pigmentation, melasma and chloasma

Find the Mesox treatment that’s right for you

Mesox Aminoacids

Mesox Aminoacids

Formula created by the triple helix of collagen. Nourishes the fibroblast for the synthesis of collagen and other proteins. Indications: induction of protein synthesis of collagen, complement of growth factor inducing therapies, maintenance of results of therapies applied at other levels of cutaneous ageing.

Mesox PPC (Phosphatidylcholine)

Mesox PPC (Phosphatidylcholine)

Mesox PPC is the product specially indicated for localised fat and mesolipolysis. Indications: localised fat accumulation, mesolipolysis treatment.

Mesox Vitamin

Mesox Vitamin

150 components constitute this powerful revitaliser of the skin. Mesox Vitamin is also the basis for any other aesthetic mesotherapy solution. Indications: dry and devitalised skin, prevent first signs of ageing, base for any other aesthetic mesotherapy solution.

Mesox White

Mesox White

Active mesotherapy against stains, dark circles and uneven skin tone. Indications: increased pigmentations, melasma, chloasma, age spots, uneven skin tone, dark circles under eyes. Complementary activity: anti-ageing.

Mesox Slimming

Mesox Slimming

Effective mesotherapy for increased drainage, in the treatment of cellulite and localised fat. Indications: cellulite, liposculpture, localised fat.

Mesox Stretch Marks

Mesox Stretch Marks

Mesotherapy for the treatment of stretch marks and scars. Indications: newly formed stretch marks, old rough stretch marks, prevent stretch mark appearance, scar reduction.

Meso Ox Hair

Meso Ox Hair

Advanced scalp treatment for hair vitality and health. Strengthens hair follicles and improves scalp health. Indications: hair loss, thinning hair, androgenetic alopecia, telogen effluvium, dandruff and seborrhea.

Mesox Firming

Mesox Firming

A complete treatment to prevent skin atonia, strengthening firmness of skin and reversing skin sagging. Indications: prevention of skin atonia, strengthening firmness of skin, reversing skin sagging.

Mesox Antiaging

Mesox Antiaging

Mesotherapy indicated in cases of thinning of the skin, loss of tone and elasticity of the skin, as well as for the treatment of wrinkles. Indications: loss of skin tonicity and elasticity, thinning of the dermis, wrinkles.

Mesox Hyaluronidase

Mesox Hyaluronidase

Post-filler hyaluronidase in case of adverse results of hyaluronic acid results. Indications: post-filler.

Mesox Hyal

Mesox Hyal

A complete treatment in case of brightness and tone loss, wrinkles and superficial lines, dry or irritated skin and skin photoageing. Indications: loss of glow, loss of tone, superficial lines and wrinkles, dry skin, irritated skin, sensitive skin, photoageing.

Meso Ox Enzymes

Meso Ox Enzymes

Enzymatic anti-cellulite treatment for smoother, firmer skin. Collagenase enzymes break down structural collagen into smaller fragments that the body naturally eliminates, reducing the appearance of cellulite and stimulating new collagen production. Indications: cellulite, uneven skin texture, loss of firmness.

Our Most Popular Treatments
Exo Ox

Exo Ox

High-concentration plant-based exosomes for advanced skin regeneration. Lyophilised Centella Asiatica exosomes combined with a hyaluronic acid solution, with 75 billion particles — the highest concentration on the market. Enhances skin appearance, promotes deep hydration, stimulates cellular regeneration and combats signs of ageing in the skin and hair.

Mesox PDRN + Niacinamide

Mesox PDRN + Niacinamide

A regenerative mesotherapy formula combining PDRN with niacinamide and three molecular weights of hyaluronic acid. Indications: dull or tired-looking skin, loss of tone and hydration, uneven texture, skin in need of repair and revitalisation.

Exo Ox Hair

Exo Ox Hair

Advanced scalp and hair treatment with plant-based exosomes and a specialised peptide complex. Combines 75 billion lyophilised plant-based exosomes with the Regecapil (P4aa) peptide complex to nourish the scalp, strengthen hair fibres, stimulate growth and protect against environmental damage.

Important

Treatment Area Sizes

The amount of product used depends on the size of the area being treated. Your practitioner will assess your needs and recommend the right amount for the best results.

Small Area

(Max 2.5ml)

To choose between e.g. under eyes, lips, chin, side of the eyes, e.g. for hair — crown area, receding hairline etc, or any other similar size.

Under Eyes
Lips
Hair (Small Area)
Close-up of the under-eye area

Medium Area

(Max 5ml)

To choose between e.g. full face, neck, hands, scalp, or any other similar size.

Full Face
Neck
Hands
Scalp
Close-up of the neck and jawline area

Large Area

(Max 10ml)

To choose between e.g. full abdomen, inner thighs, full scalp, or any other similar size.

Abdomen
Inner Thighs
Full Scalp
Close-up of the abdomen area

Frequently Asked Questions

Everything you need to know about mesotherapy at YourHealthFirst Clinic.

A course of 6–8 sessions is advised every two weeks for the first time, with maintenance treatments 1–2 times a year.

Skin will become more radiant, hydrated, nourished and firmer with an improved texture. Mesotherapy can also improve dull, tired-looking skin and superficial wrinkles.

The formula is bespoke to your concern — Mesox Aminoacids, PPC, Vitamin, White, Slimming, Stretch Marks, Hair, Firming, Antiaging, Hyaluronidase and Hyal formulas are available, each targeting a specific skin, body or hair concern.

Treatment time takes approximately thirty minutes and whilst not painful, it can be slightly uncomfortable, so an anaesthetic cream can be used if the skin is a little sensitive.

With minimal downtime, a little bruising and swelling may occur, but it will be short-lived and should settle within 24 hours.

Yes — mesotherapy can be used to remove fat in areas like the stomach, thighs, buttocks, hips, legs, arms and face, reduce cellulite and stretch marks, and treat alopecia, all delivered with the same precise micro-injector.

Adults with dull, dehydrated or uneven skin, acne scarring, fine lines, stretch marks or hair loss who want a customised, multi-ingredient approach to skin, body or hair improvement.

Get an Appointment

By phone: 0207 225 3582 / 078 1847 4041
By email: info@yourhealthfirst.uk

Opening Hours

Monday – Friday — 10am to 6pm
Saturday — 12pm to 4pm (doctor appointments only)
Sunday & out of hours — by appointment only

Wigmore Medical & British Association of SclerotherapistsBGi UK Insurance Risk ManagementCPD AccreditedCity of Westminster Training Certification ServiceCPD MemberWomen Excellence AwardWAW Hall of FameSoMUKNational Phlebotomist Register